COVID-19: ACE, Targeted Therapies, Old & New Medicines

Antimicrobial Regeneration Consortium LogoThis episode talks about research about COVID-19, angiotensin converting enzyme (ACE), and targeted therapies, and our feature is an interview with CU-Boulder scientists Anushree Chatterjee and Prashant Nagpal. This husband and wife science team explains why there may be a downside to adapting old medications to fight Covid-19.  They’ll also explain their anguish about why creating new “drugs” to fight Covid-19 cannot happen as fast as they or anyone would like.  They have founded the Antimicrobial REgeneration Consortium, with the goal of speeding up the creation and availability of antimicrobial medicines.  They are also developing a way to give people a tiny dose of nanoparticles–basically incredibly tiny microchips, preprogrammed to specifically target a disease such as Covid-19  (see our earlier discussions with them).

Host: Beth Bennett, Angele Sjong, Shelley Schlender, Joel Parker
Producer: Joel Parker, Beth Bennett
Engineer: Maeve Conran
Executive Producer: Joel Parker

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Miracle Brew (encore feature) // COVID-19 // Drying Towels

This week on How On Earth, we present an Encore Feature from January 2018 about the science and art of brewing beer with guest Pete Brown, author of Miracle Brew.  This episode also includes new headlines about current research about COVID-19 and about the science of drying towels outside.

Host: Beth Bennett
Producer: Joel Parker, Beth Bennett
Engineer: Maeve Conran
Additional contributions: Angele Sjong
Executive Producer: Beth Bennett

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CoVid19 Update // Sleep and Your Immune System

man-in-bed-struggling-to-sleep-wd-noexp-620x400This week on How On Earth, we produced the entire show out of the studio, explaining one brief glitch. Beth gives a short update on the way the corona virus infects cells and how this entry point can affect people taking blood pressure medications. In our feature interview, Beth talks with Professor Mark Opp, who studies sleep in his lab at the University of Colorado here in Boulder (interview starts at about 10 minutes). He’s especially interested in the interaction between sleep and our immune systems. Not that long ago, people didn’t think there was any relationship between the two, but our understanding of both systems has evolved.

Host: Beth Bennett
Producer: Beth Bennett
Engineer: Maeve Conran
Additional contributions: Angele Sjong
Executive Producer: Beth Bennett

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Peer Pressure can Influence Your Carbon Footprint // CoVid19 Update

9780691193083This week on How on Earth we start with an update on the corona virus, focusing on treatments and vaccines. At 12 minutes, we begin our interview with Bob Frank, author of Under the Influence, Putting Peer Pressure to Work. This book explains how we could redirect trillions of dollars annually in support of carbon-free energy sources, all without requiring painful sacrifices from anyone. Dr Frank has developed some novel strategies relying on peer pressure to get people to change their actions so as to reduce carbon emissions and climate change. He also details many prior and successful examples of this type of peer pressure. You can see more at the publisher’s website.

Hosts: Beth Bennett & Angele Sjong
Producer: Beth Bennett
Engineer: Beth Bennett
Additional Contributions: Angele Sjong
Executive Producer: Beth Bennett

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The Science of Hearing and Hearing Aids

Volume Control
Volume Control

This week Beth and Angele talk with David Owen about his book, Volume Control, in which he explores the surprising science of hearing and the remarkable technologies that can help us hear better. In the book, he argues that failing to take care of our hearing comes with a huge social cost. He demystifies the science of hearing while encouraging readers to get the treatment they need for hearing loss and protect the hearing they still have.

Executive Producer: Beth Bennett
Producer: Beth Bennett & Angele Sjong
Headlines: Beth Bennett & Angele Sjong
Engineer: Beth Bennett

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Who Pays for Climate Change?

merlin_166536642_24b1e96c-327a-4b9c-9979-f87ed8a0b502-articleLargeThis week, Beth and Angele speak with with Brenda Ekwurzel in the studio. Brenda is the director of climate science for the Union of Concerned Scientists. She was in Boulder for a panel on Air Quality and Climate Change. She spoke about some Colorado issues e.g. wildfire and drought, and assigning responsibility for specific events to fossil fuel producers. She is a widely quoted expert on climate change, and co-authored the UCS guide Cooler Smarter: Practical Steps for Low-Carbon Living. For more information you can visit her website.

Hosts: Angele Sjong and Beth Bennett
Producers: Angele Sjong and Beth Bennett
Engineer: Beth Bennett
Executive Producer: Beth Bennett

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Ketogenic Diet and Muscle and Memory

Fat MouseThis week on How on Earth, we speak with Dr John Newman, geriatrician and geoscientist at the Buck Institute. He describes his recent research in mice, showing that both memory and muscle improve in animals eating a high fat diet. To see more details on these experiments, you can visit the lab website.
To register for the Air Quality and Climate Conference, send an email to sstrife@bouldercounty.org

Hosts: Angele Sjong & Beth Bennett
Producer: Beth Bennett
Engineer: Maeve Conran
Executive Producer : Beth Bennett

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Top Stories of the Decade

Black Hole Image from New Scientist
Black Hole Image from New Scientist

This week on How on Earth, Angele and Beth distill some of the top science news of the past year and decade, ranging from the first image of a black hole, as seen here, to DNA sequencing of ancient genomes, some new hominid ancestors, advances in AI, and more!

Hosts: Beth Bennett & Angele Sjong
Producer: Beth Bennett & Angele Sjong
Engineer: Beth Bennett
Executive Producer: Joel Parker

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Cognitive Brain Development in Adolescents, Part 2

Prof Marie Banich
Prof Marie Banich
Four years ago Beth interviewed Professor Marie Banich, a neuroscience researcher at the University of Colorado here in Boulder. She had just received a major grant from NIH to characterize how brain regions involved in decision making and judgment change as children grow up. In the past four years she has assembled a multi-site team of neuroscientists and experts in developmental psychology who have begun testing the 11,000+ 8-10 year olds enrolled in the massive study. To find more detail, see her lab website (https://www.colorado.edu/faculty/banich/research/research-interests).
Hosts: Beth Bennett & Angele Sjong
Producer: Beth Bennett
Engineer: Beth Bennett
Executive Producer: Joel Parker
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Alzhieimer’s Drug Reverses Brain Damage Caused by Binge Drinking

Drinking in Rats
Drinking in Rats

Beth interviews neuroscientist and addiction researcher Scott Swartzwelder who talks about his research on reversing alcohol-induced brain damage in young rats. In past work, Professor Swartzwelder and colleagues have identified specific areas of the brain damaged by drinking, especially in adolescent rats. In this interview, he describes, how this damage occurs, and amazingly, how treatment later in life can actually reverse it.

Hosts: Beth Bennett & Angele Sjong
Producer: Beth Bennett
Engineer:Beth Bennett
Additional Contributions: Angele Sjong
Executive Producer: Joel Parker

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