Zika Update

CDC targets Zika
CDC targets Zika
In headlines and 2 interviews with Zika researchers,Beth covers new material on this disturbing disease. CDC Chief of Virology, Dr Ann Power (start time 3’45”) and Dr Rushika Ferrara of CSU (start time 10’45”), describe aspects of the viral life cycle, including transmission, symptom variability, and promising avenues leading to potential treatments and preventions. For more information, cdc.gov and http://source.colostate.edu/dancing-through-the-lab-no-but-science-requires-fancy-footwork/; also http://www.ancestralhealth.org/
Host: Beth Bennett
Producer: Beth Bennett
Engineer: Maeve Conran
Additional Contributions: Shelley Schlender
Executive Producer: Susan Moran
Listen to the show:

Play

Exploring your DNA // Cellular Innards Revealed

Genomic exploration by Carl Zimmer
Genomic exploration by Carl Zimmer
This week on How on Earth we speak with 2 notables. NY Times columnist Carl Zimmer describes his exploration of his genome sequence, yes all 3 billion bases! See the series he has produced detailing this journey at https://www.statnews.com/feature/game-of-genomes/season-one/. Then, local cell biologist Gia Voeltz studies how the endoplasmic reticulum (ER) is formed. It is a large continuous structure in the cell, with many different functions and an elaborate shape. The ER was long thought to be the site of synthesis of proteins and other large biologically important molecules. Work in the Voeltz lab has expanded its role considerably. Visit her website to see beautiful moving pictures of ER in action: http://www.voeltzlab.org/#!research-projects/c10g1
Host: Beth Bennett
Producer: Beth Bennett
Engineer: Maeve Conran
Executive Producer: Susan Moran
Listen to the show:

Play

Diatoms: Ecology and Aesthetics

An example of the 'glass house'
An example of the ‘glass house’
Beth interviews Dr Sarah Spaulding, of the Institute for Arctic and Alpine Research here in Boulder. Sarah studies microscopic single celled algae, creatures that photosynthesize but aren’t plants. She discusses their ecological roles in numerous ecosystems as well as challenges in identifying them and her long term goals in studying these elusive but ubiquitous creatures. See more at https://westerndiatoms.colorado.edu/
Host: Beth Bennett
Producer: Beth Bennett
Engineer: Maeve Conran
Executive Producer: Shelley Schlender
Listen to the show:

Play

A History of Water in Colorado’s Front Range

land made of waterHost Beth Bennett interviews Bob Crifasi, author of A Land Made of Water (starts at 4’55”). Bob works in water management and planning and is an environmental scientist with over 25yr experience. He was the Water Resources Administrator for the city of Boulder’s Open Space and Mountain Parks Dept. He has served on board of directors of 11 ditch companies and as the president of several, supervising all aspects of ditch operation.

Hosts: Beth Bennett, Alejandro Soto
Producer: Beth Bennett
Engineer: Maeve Conran
Additional contributions: Shelley Schlender
Executive Producer: Shelley Schlender

Listen to the show:

Play

How the Glucocorticoid Receptor can Treat Asthma, Cancer, and More

What the mysterious acronym means
What the mysterious acronym means

The Glucocorticoid Receptor (starts at 5:30): We interview Dr. Miles Pufall who studies the glucocorticoid receptor, a protein in cell membranes that is the target of drugs used to treat a variety of conditions from asthma to cancer. Binding cortisol causes the receptor to be moved to the nucleus where it turns on (or off) numerous genes. One of the big questions is how does each cell type ‘know’ which genes should be targeted?

Hosts: Beth Bennett, Joel Parker
Producer: Beth Bennett
Engineer: Beth Bennett
Additional Contributions: Joel Parker, Susan Moran
Executive Producer: Joel Parker

Listen to the show:

Play

Using the Microbiome to Determine Time of Death

MicrobiomeUsing the Microbiome to Determine Time of Death (starts at 5:40): This week on How on Earth, we speak with Jessica Metcalf, an evolutionary biologist, who studies bacteria, specifically the microbiome. One of her research interests is using molecular biology to address basic hypotheses about the role of microbes in corpse decomposition. The time since death, or postmortem interval, also known as (PMI), is important for criminal investigations because it can lead to the identification of the deceased and validate alibis. PMI is critical to both forensic science and pop culture (e.g. TV shows Bones, CSI). Recently she co-authored a paper published in Science, describing how various species of the microbiome can be used to accurately and repeatedly determine the post-mortem interval.

Host: Beth Bennett
Producer: Beth Bennett
Engineer: Maeve Conran
Executive Producer: Joel Parker

Listen to the show:

Play

What You Can Do About Global Warming

solar-panels What You Can Do About Global Warming (starts at 5:20): We interview Craig Hover, author of A World to Come Home To: Ending Global Warming in Our Lifetime. Craig is a licensed professional engineer with more than 30 years of engineering, project and facilities management, financial services and consulting. In his book he lays out a comprehensive vision of implementing sustainable strategies for reducing carbon emissions and reversing the current trends in climate change.

Host: Beth Bennett
Producer: Beth Bennett
Engineer: Maeve Conran
Additional contributions: Shelley Schlender
Executive Producer: Beth Bennett

Listen to the show:

Play

How the Brain Matures

The teenaged brain is wired differently than the adult.
The teenaged brain is wired differently than the adult.

Brains (starts at 4:35) This week on How on Earth we interview Professor Marie Banich, from the University of Colorado here in Boulder. Dr Banich uses cutting edge methodologies, particularly structural and functional MRI, to examine the role of the prefrontal cortex, as well as other brain regions, in executive function. Today she tells us about work that was recently funded by NIH to characterize how these systems change over the course of development.

Hosts: Beth Bennett and Joel Parker
Producer: Beth Bennett
Engineer: Joel Parker
Executive Producer: Beth Bennett

Listen to the show:

Play

Are GMOs Environmentally-friendly?

Genetically-modified crops
Genetically-modified crops

GMOs (start time 5:35) An interview with Dr Sharon Collenge, an ecologist at the University of Colorado. Dr Collenge is an advocate of using new genetic technologies to make slight modifications to plant genomes which can increase yield, protect against disease and reduce pesticide use.

Host: Beth Bennett
Producer: Beth Bennett
Engineer: Maeve Conran
Additional contributions: Joel Parker, Beth Bennett
Executive Producer: Beth Bennett

Listen to the Show:

Play

Neurobiology of Alcohol Abuse

Raising drinking glasses to celebrate - drinking? Image courtesy of Huffington Post
Raising drinking glasses to celebrate – drinking?
Image courtesy of Huffington Post

This week on How on Earth, we speak with Dr Paula Hoffman, a neuropharmacologist – she’s scientist who studies what drugs do in the brain- who works on the genetics of alcohol and other drugs of abuse. Paula reviews the action of alcohol on different neurotransmitter systems of the brain then describes some of the genetic issues which predispose people to risk for becoming alcoholics. Finally she talks about research done in her lab which has resulted in preliminary understanding of genetic networks involved.

Host: Beth Bennett
Producer: Beth Bennett
Engineer: Maeve Conran
Executive Producer: Susan Moran

Listen to the show:

Play