Can Covid-19 Affect Your Mitochondria?

Mitochondria
Mitochondria
Beth talks with Steven Engle, Chief Executive Officer and Director of CohBar, Inc, a biotechnology company developing mitochondria-based therapeutics to treat chronic diseases and extend healthy lifespan. The company’s lead compound, CB4211, is in early stage clinical trial for fatty liver disease and obesity. The company also has four preclinical programs, two in cancer, one in fibrotic diseases, one in type 2 diabetes, and one, which we discuss here, in COVID-19 associated acute respiratory syndrome. You can find more at the company website. The interview starts at about 6 minutes.
Host:Beth Bennett
Executive Producer: Beth Bennett
Show Producer: Beth Bennett
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COVID-19: The Evidence for Aerosol Transmission & Implications for Containment

This week How on Earth producer Beth Bennett spoke with Professor Jose Jimenez, a professor in the Chemistry Dept here at CU in Boulder. His research background for over two decades has focused on detecting and measuring aerosols. Recently he became involved in applying this expertise to the question of how the corona virus is transmitted. He and his team have developed a model that predicts the likelihood of transmission of the virus from an infected person to other people in an indoor space. Here are find links to the model, a webinar describing its development and use and his website. The interview starts at ~8 min.

Executive Producer: Susan Moran
Show Producer: Beth Bennett
Additional Contributions: Joel Parker
Engineer: Maeve Conran

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COVID-19: ACE, Targeted Therapies, Old & New Medicines

Antimicrobial Regeneration Consortium LogoThis episode talks about research about COVID-19, angiotensin converting enzyme (ACE), and targeted therapies, and our feature is an interview with CU-Boulder scientists Anushree Chatterjee and Prashant Nagpal. This husband and wife science team explains why there may be a downside to adapting old medications to fight Covid-19.  They’ll also explain their anguish about why creating new “drugs” to fight Covid-19 cannot happen as fast as they or anyone would like.  They have founded the Antimicrobial REgeneration Consortium, with the goal of speeding up the creation and availability of antimicrobial medicines.  They are also developing a way to give people a tiny dose of nanoparticles–basically incredibly tiny microchips, preprogrammed to specifically target a disease such as Covid-19  (see our earlier discussions with them).

Host: Beth Bennett, Angele Sjong, Shelley Schlender, Joel Parker
Producer: Joel Parker, Beth Bennett
Engineer: Maeve Conran
Executive Producer: Joel Parker

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Miracle Brew (encore feature) // COVID-19 // Drying Towels

This week on How On Earth, we present an Encore Feature from January 2018 about the science and art of brewing beer with guest Pete Brown, author of Miracle Brew.  This episode also includes new headlines about current research about COVID-19 and about the science of drying towels outside.

Host: Beth Bennett
Producer: Joel Parker, Beth Bennett
Engineer: Maeve Conran
Additional contributions: Angele Sjong
Executive Producer: Beth Bennett

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