Clinical Trials Test MDMA as PTSD Treatment

Artwork credit: MDMA trial participant Allison Heistand-Phelps

Artwork credit: MDMA trial participant Allison Heistand-Phelps

This week on How on Earth host Susan Moran interviews two investigators of FDA-approved clinical trials testing the efficacy and safety of the illegal drug MDMA — known in an altered form as Ecstasy or Molly — as a treatment (along with psychotherapy sessions) for Post-Traumatic Stress Syndrome. Our guests are Marcela Ot’alora and Bruce Poulter, investigators of the Colorado trial. Marcela is a licensed psychotherapist and Bruce is a registered nurse with a masters degree in public health

PTSD is an anxiety disorder that affects up to one in 12 people in the United States, and it’s at least as common in some other countries. It is a serious, and costly, public health problem. If the trials are successful,  MDMA, which has its critics, could become commercially available as a medically prescribed treatment by 2021. The trials are being funded by a nonprofit organization, the Multidisciplinary Association for Psychedelic Studies (MAPS), which promotes careful and beneficial uses of psychedelics and marijuana.

Hosts: Susan Moran, Joel Parker
Producer: Susan Moran
Engineer: Joel Parker
Executive Producer: Joel Parker

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Suggestible You: How Our Brain Tricks Us

sug_you_subtleo_yellow1-647x580The Science of Suggestibility (start time: 5:00) Scientists are learning more and more about how our expectations and beliefs influence how our bodies, including our neurochemistry, respond to pain and disease. The researchers are discovering that we are very suggestible creatures. But we are not all equally suggestible. Some of us can cure serious ailments even when we’ve knowingly taken a placebo remedy, but others can not. Herein lies a major puzzle that vexes drug manufacturers and medical practitioners. It’s a puzzle that has intrigued Erik Vance, a science journalist, since he nearly died from a severe illness when he was a toddler. His journey is detailed in a book that was just published today. It’s called Suggestible You: Placebos, False Memories, Hypnosis and the Power of Your Astonishing Brain (National Geographic).  Listen to How On Earth’s Susan Moran’s interview with Erik Vance.

Hosts: Susan Moran, Alejandro Soto
Producer: Susan Moran
Engineer: Maeve Conran
Executive Producer: Beth Bennett

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