How the Glucocorticoid Receptor can treat asthma, cancer, and many other conditions.

What the mysterious acronym means

What the mysterious acronym means

Beth interviews Dr Miles Pufall who studies the glucocorticoid receptor, a protein in cell membranes that is the target of drugs used to treat a variety of conditions from asthma to cancer. Binding cortisol causes the receptor to be moved to the nucleus where it turns on (or off) numerous genes. One of the big questions is how does each cell type ‘know’ which genes should be targeted?
Hosts:Beth Bennett and Joel Parker
Producer:Beth Bennett
Engineer:Beth Bennett
Additional Contributions:Joel Parker and Susan Moran
Executive Producer:Joel Parker
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Winter Stars // Pollinators and Insecticides

Sky_MilkyWay_BearLake_300x300Winter Stars (starts at 5:30).  We talk with Dave Sutherland, an Interpretive Naturalist with Boulder Open Space and Mountain Parks, about winter star-gazing.  This program is tied to an upcoming concert performance by the Boulder Philharmonic Orchestra on February 12, 2016.  More information about the Boulder night hikes and other programs can be found at:  www.naturehikes.org and to find out more about for the starry concert and to purchase tickets, check out http://boulderphil.org/site/concerts/spheres-of-influence

neonicotinoids-BACHMANS-2014Pollinators and Insecticides (starts at 10:06).  Although they may be hidden in the chill of winter, crickets, bees and thousands of other insects play a critical role year-round in how we grow the food we eat. Dr. Jonathan Lundgren, a South Dakota-based entomologist, talks with host Susan Moran about how predator insects serve as biological pest controls. Dr. Lundgren’s research on adverse effects of a controversial class of insecticides, called neonicotinoids, on pollinators such as honeybees and monarch butterflies,  has made him the target of political pressure from his employer, the U.S. Department of Agriculture. A watchdog group has filed a whistleblower complaint on Lundgren’s behalf against the USDA. Dr. Lundgren recently started a research and education farm, called Blue Dasher Farm, which promotes regenerative agriculture.

Hosts: Susan Moran, Joel Parker
Producer & Engineer: Joel Parker
Executive Producer: Joel Parker

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Electric Car Road Trips // Renewable Energy Nation . . . in 15 Years

Tesla Superchargers - Rural Arizona

Tesla Superchargers – Rural Arizona

Electric Car Road Trips (starts 3:42): We go on a road trip with How on Earth’s Shelley Schlender to see how all-electric vehicles are exceeding “range anxiety” by driving coast to coast, all on electricity.  Along the way we talk with Boulder Nissan’s Nigel Zeid about regional plans to help more drivers “plug in” and with Hunter Lovins, head of Natural Capitalism Solutions.

courtesy Solar Praxis

courtesy Solar Praxis

Renewable Energy Nation (starts 11:53): Joel Parker talks live with NOAA scientist Alexander MacDonald and Christopher Clack, a mathematician at the University of Colorado-Boulder. They have developed a model that demonstrates how the entire U.S. can run on solar and wind power–with existing technologies, with no batteries, and at lower cost than today’s prices–within 15 years. For more information, see this video and these animations of:
U.S. Wind Power Potential
U.S. Solar Power Potential
U.S. Power Flow

Hosts: Joel Parker, Beth Bennett
Producer: Shelley Schlender
Executive Producer: Joel Parker
Engineer: Shelley Schlender
Additional Contributions: Susan Moran

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Using the Microbiome to Determine Time of Death

MicrobiomeThis week on How on Earth, we speak with Jessica Metcalf, an evolutionary biologist, who studies bacteria, specifically the microbiome. One of her research interests is using molecular biology to address basic hypotheses about the role of microbes in corpse decomposition. The time since death, or postmortem interval, also known as (PMI), is important for criminal investigations because it can lead to the identification of the deceased and validate alibis. PMI is critical to both forensic science and pop culture (e.g. TV shows Bones, CSI). Recently she co-authored a paper published in Science, describing how various species of the microbiome can be used to accurately and repeatedly determine the post-mortem interval.

Host: Beth Bennett
Producer: Beth Bennett
Engineer: Maeve Conran
Executive Producer: Joel Parker

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Hubble Space Telescope

Unknown

Today’s show of How on Earth starts with headlines about dark matter, genetic mysteries, jealous monkeys, and polar bears.  We then present a short feature of BBC’s Science in Action about the Hubble Space Telescope.

This is shorter than our usual How on Earth show due to technical difficulties with the phone system for our feature interview with entomologist Jonathan Lundgren; that feature will appear in a future show.

Hosts: Susan Moran, Joel Parker
Producer: Susan Moran
Executive Producer and Engineer: Joel Parker
Headline Contributions: Susan Moran, Beth Bennett, Joel Parker

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Hunter Lovins – Regenerative Economics Extended Version

Hunter Lovins - Natural Capitalism Solutions

Hunter Lovins – Natural Capitalism Solutions

Hunter Lovins – Regenerative Economics EXTENDED VERSION.  This is the extended version of the fall 2015 talk by Hunter Lovins, recorded by Shelley Schlender. Lovins heads up Natural Capitalism Solutions, and she’s a sought after speaker around the world, as well as here in Colorado. She gave this talk, including visuals, and called it Regenerative Economics.  This talk was recorded in Boulder as part of the Colorado Chautauqua Events series, in conjunction with the Boulder City Club.

For the broadcast version of this talk, GO HERE.

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Our Microbes, Ourselves — Special Call-in Show

human gut microbes

human gut microbes

Our Microbes, Ourselves, Dec. 31, 2015: Roughly one hundred trillion bacteria are living, and gorging, in our gut–all the more so during the indulgent holidays. Microbes influence our health and well-being, by affecting our gut directly, as well as the crops we eat and the soils in which we grow crops. These microbial communities  – called the gut microbiome — have been linked to many disorders, including obesity, inflammatory bowel disease, diabetes, cancer, immune disorders, and even mental illness. We are just at the dawn of a new era of microbial treatments for many illnesses. After a recent How On Earth show generated so much interest, we decided to bring our guest, Amy Sheflin, back for an hour-long call-in show on A Public Affair on KGNU. Amy is a doctoral student at Colorado State University in food science and human nutrition. She studies how the food we eat alters the microbial communities in our gut, and how those microbes in our bodies influence our overall health. For more info on the gut microbiome, check out Amy’s favorite books on the topic: The Good Gut, by Justin and Erica Sonnenburg; and The Inside Tract, by Gerard Mullins. Also check out the American Gut Project.

Host: Susan Moran
Engineer: Maeve Conran

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Hunter Lovins – Regenerative Economics for the Future of Humanity

Hunter Lovins - Natural Capitalism Solutions

Hunter Lovins – Natural Capitalism Solutions

Hunter Lovins – Regenerative Economics (Starts 2:42) One of the world’s leading voices for the environment is urging the world to work for even more than a sustainable economy.  She says it’s time for a regenerative economy.  That’s the message from Boulder County resident, Hunter Lovins.  Lovins heads up Natural Capitalism Solutions, and she’s a sought after speaker around the world, as well as here in Colorado.  To give you an idea about what the vision of Lovins for a regenerative economy, here is an excerpt from a recent talk about the Future of Humanity.  This talk was recorded in Boulder as part of the Colorado Chautauqua Events series, in conjunction with the Boulder City Club.

For the extended version of this talk, go here.

Host: Kendra Krueger
Producer: Shelley Schlender
Engineer: Kendra Krueger
Executive Producer: Beth Bennett

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Climate Change and Cities

Climate Change and Cities (starts at 5:05)  Sea level rise, severe storms, heat waves – these are just a few of the challenges cities might be facing as the climate changes in the next few decades.  So how should they adapt to cope with such events? And with urban developments being one of the largest contributors to greenhouse gas emissions, what can they do to mitigate their impact?

paty2 2010These are questions that the Urban Climate Change Research Network has set out to address in its Second Assessment Report on Climate Change and Cities.  The report gives the expected climate projections for 100 cities along with guidance on increasing resilience and reducing impact.  The Network released its summary for city leaders at the Paris talks only three weeks ago, and Boulder’s Paty Romero Lankao was there to promote the report — she was a co-editor of the report and coordinating lead author of the chapter on governance. Dr. Lankao is a research scientist at the National Center for Atmospheric Research who investigates the interactions between urban development and global environmental change, and in our show she talks with us about the outlook for cities and the report.

HostsJane Palmer, Joel Parker
Producer and Engineer: Joel Parker
Executive Producer: Beth Bennett
Headline Contributions: Susan Moran, Beth Bennett, Jane Palmer

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What you can do about global warming

solar-panelsBeth interviews Craig Hover, author of A World to Come Home To: Ending Global Warming in Our Lifetime. Craig is a licensed professional engineer with more than 30 years of engineering, project and facilities management, financial services and consulting. In his book he lays out a comprehensive vision of implementing sustainable strategies for reducing carbon emissions and reversing the current trends in climate change.
Host: Beth Bennett
Producer: Beth Bennett
Engineer: Maeve Conran
Additional contributions: Shelley Schlender
Executive Producer: Beth Bennett
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